Venema F, Dröge MJ, van Hattum JJC, Oosting E.
A sensitive LC-MS/MS method for the quantitive determination of dexamethasone in porcine plasma and porcine muscle, liver and kidney tissue
10th European Association for Veterinary Pharmacology and Toxicology. Turin, Italy. September 17-22, 2006
The ultimate goal of our work was to develop and validate a sensitive and reliable bioanalytical LC-MS/MS method suitable for the determination of dexamethasone in porcine muscle, liver and kidney tissue and in porcine plasma. A full validation of the method was performed. A sensitive bioanalytical LC-MS/MS method for the quantitative determination of dexamethasone in porcine plasma, muscle, liver and kidney tissue has been developed and validated successfully.